Nevraplus is as a formulation with triple antioxidant action has been purposely designed in order to address the needs of patients with chronic pain and peripheral neuropathy. Chronic pain is characterized by pain that persists over time (6 months) and in most cases is continuous day and night. These patients are in need not only of a temporary relief, but also of consecutive handling. Nevraplus, is produced with a controlled release technology (retard form) that permits the maintenance of active ingredients in blood circulation at stable quantities, resulting in a prolonged treatment duration and pain alleviation. Aside of 5000+ bibliography articles on ALA (PubMed) as well as the FDA guidelines proposing the use ALA products on Diabetic neuropathic pain, Nevraplus, is backed by further strong scientific evidence regarding its efficacy on pain conditions. A clinical study on 72 patients with diabetic neuropathy, showed that the daily administration of 600 mg of ALA, significantly reduced the symptoms of neuropathy and improved daily life. ALA has been further studied for its positive effect on chronic pain, low back pain, radiculopathy, cervical syndrome and carpal tunnel syndrome conditions.